STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KUO02180.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)    
Predicted Functional Partners:
KUO02178.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.810
KUO02177.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.800
KUO02179.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
0.796
KUO02181.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.793
gyrB
DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.603
KUN95060.1
DNA gyrase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.603
KUN90843.1
DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.603
KUN99631.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.418
KUN98875.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.418
KUN96415.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.418
Your Current Organism:
Streptomyces resistomycificus
NCBI taxonomy Id: 67356
Other names: ATCC 19804, BCRC 13755, CBS 556.68, CCRC 13755, CCRC:13755, DSM 40133, IFO 12814, ISP 5133, JCM 4409, NBRC 12814, NCIMB 9843, NRRL 2290, NRRL-ISP 5133, PCM 2296, S. resistomycificus, Streptomyces sp. USC032, UNIQEM 190
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.