Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KUO01331.1Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)    
Predicted Functional Partners:
KUO01332.1
Citrate (pro-3S)-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
 
 
 0.972
KUO01858.1
crotonyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.972
KUO01330.1
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.945
KUO01333.1
Protein meaA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.944
KUN90575.1
Phosphopantetheine-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.842
KUN90579.1
Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.837
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
  0.831
sucC-2
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
  0.831
KUN90588.1
Modular polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.831
KUN90589.1
Acyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.831
Your Current Organism:
Streptomyces resistomycificus
NCBI taxonomy Id: 67356
Other names: ATCC 19804, BCRC 13755, CBS 556.68, CCRC 13755, CCRC:13755, DSM 40133, IFO 12814, ISP 5133, JCM 4409, NBRC 12814, NCIMB 9843, NRRL 2290, NRRL-ISP 5133, PCM 2296, S. resistomycificus, Streptomyces sp. USC032, UNIQEM 190
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