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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KUO01332.1Citrate (pro-3S)-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (319 aa)    
Predicted Functional Partners:
KUO01331.1
Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.978
KUN93823.1
Citrate lyase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
  
  
 
0.956
KUO01333.1
Protein meaA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.936
KUO01858.1
crotonyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.936
KUO01330.1
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.914
KUO01271.1
Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family.
    
 0.879
KUN98848.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.870
KUN91942.1
methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.870
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
    
 0.861
KUN92175.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.859
Your Current Organism:
Streptomyces resistomycificus
NCBI taxonomy Id: 67356
Other names: ATCC 19804, BCRC 13755, CBS 556.68, CCRC 13755, CCRC:13755, DSM 40133, IFO 12814, ISP 5133, JCM 4409, NBRC 12814, NCIMB 9843, NRRL 2290, NRRL-ISP 5133, PCM 2296, S. resistomycificus, Streptomyces sp. USC032, UNIQEM 190
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