STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KUN95930.1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)    
Predicted Functional Partners:
rsmA
Hypothetical protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.904
KUN96055.1
Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.878
ispE
4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
     
 0.869
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
   0.849
KUN95929.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.822
rsmI
uroporphyrin-III methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
  
    0.721
KUN95933.1
Glycerophosphodiester phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.694
KUN95927.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.674
ffh
Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
   
 0.585
secA
Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
 
   
 0.573
Your Current Organism:
Streptomyces resistomycificus
NCBI taxonomy Id: 67356
Other names: ATCC 19804, BCRC 13755, CBS 556.68, CCRC 13755, CCRC:13755, DSM 40133, IFO 12814, ISP 5133, JCM 4409, NBRC 12814, NCIMB 9843, NRRL 2290, NRRL-ISP 5133, PCM 2296, S. resistomycificus, Streptomyces sp. USC032, UNIQEM 190
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