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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (403 aa)    
Predicted Functional Partners:
kynA
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
 
 0.997
kynA-2
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
 
 0.987
KUN10552.1
Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.949
KUN03498.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.936
KUN09459.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.890
KUN07098.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.890
KUN00179.1
Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.811
KUN10540.1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.774
KUN04952.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.752
KUN04671.1
Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family.
   
 
  0.712
Your Current Organism:
Streptomyces yokosukanensis
NCBI taxonomy Id: 67386
Other names: ATCC 25520, BCRC 11875, CBS 662.69, CCRC 11875, CCRC:11875, DSM 40224, IFO 13108, ISP 5224, JCM 4137, JCM 4559, NBRC 13108, NRRL B-3353, NRRL-ISP 5224, S. yokosukanensis, Streptomyces yokosukensis
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