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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KUN08472.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)    
Predicted Functional Partners:
KUN08471.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.759
KUN08474.1
Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.726
KUN08473.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.677
KUN03447.1
Histidine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family.
  
    0.645
KUN08218.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.604
KUN00088.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.604
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
  
  
 0.584
KUM98349.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.532
KUM99564.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.530
KUN05962.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.520
Your Current Organism:
Streptomyces yokosukanensis
NCBI taxonomy Id: 67386
Other names: ATCC 25520, BCRC 11875, CBS 662.69, CCRC 11875, CCRC:11875, DSM 40224, IFO 13108, ISP 5224, JCM 4137, JCM 4559, NBRC 13108, NRRL B-3353, NRRL-ISP 5224, S. yokosukanensis, Streptomyces yokosukensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.