close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KUN06262.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)    
Predicted Functional Partners:
KUN03854.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.923
KUN06351.1
Radical SAM domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.876
KUN08820.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.780
KUN06263.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.756
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.753
KUN04387.1
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.745
KUN09967.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 
 0.743
KUN08547.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.717
KUN06995.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
 0.709
Your Current Organism:
Streptomyces yokosukanensis
NCBI taxonomy Id: 67386
Other names: ATCC 25520, BCRC 11875, CBS 662.69, CCRC 11875, CCRC:11875, DSM 40224, IFO 13108, ISP 5224, JCM 4137, JCM 4559, NBRC 13108, NRRL B-3353, NRRL-ISP 5224, S. yokosukanensis, Streptomyces yokosukensis
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.