close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KUN04672.12-hydroxy-3-oxopropionate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)    
Predicted Functional Partners:
KUN04673.1
Hydroxypyruvate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the hyi family.
 
 0.985
KUN04669.1
Glyoxylate carboligase; Catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.
 
 
 0.913
KUN03264.1
3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.913
KUN02870.1
Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.877
KUN02872.1
3-hydroxyisobutyryl-CoA hydrolase; Catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.876
KUN06605.1
3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.863
KUN03485.1
Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family.
 
 
  0.859
KUN03327.1
2-hydroxy-3-oxopropionate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.851
KUM99659.1
Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.850
KUN08440.1
Betaine-aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.824
Your Current Organism:
Streptomyces yokosukanensis
NCBI taxonomy Id: 67386
Other names: ATCC 25520, BCRC 11875, CBS 662.69, CCRC 11875, CCRC:11875, DSM 40224, IFO 13108, ISP 5224, JCM 4137, JCM 4559, NBRC 13108, NRRL B-3353, NRRL-ISP 5224, S. yokosukanensis, Streptomyces yokosukensis
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.