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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KUN04558.1Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)    
Predicted Functional Partners:
KUN00620.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.997
KUN04559.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.984
KUN07529.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.974
KUN06612.1
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.921
KUN08707.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.904
KUN09663.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.903
KUN09746.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.902
KUN09148.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.888
KUM98341.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.883
KUN07416.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.879
Your Current Organism:
Streptomyces yokosukanensis
NCBI taxonomy Id: 67386
Other names: ATCC 25520, BCRC 11875, CBS 662.69, CCRC 11875, CCRC:11875, DSM 40224, IFO 13108, ISP 5224, JCM 4137, JCM 4559, NBRC 13108, NRRL B-3353, NRRL-ISP 5224, S. yokosukanensis, Streptomyces yokosukensis
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