close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KUN04559.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)    
Predicted Functional Partners:
KUN00620.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.996
KUN04558.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.984
KUN09664.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.932
KUN06612.1
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.883
KUN08706.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.828
KUN03284.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.826
KUN05934.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.824
KUN09148.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.822
KUN09147.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.814
KUN04560.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.797
Your Current Organism:
Streptomyces yokosukanensis
NCBI taxonomy Id: 67386
Other names: ATCC 25520, BCRC 11875, CBS 662.69, CCRC 11875, CCRC:11875, DSM 40224, IFO 13108, ISP 5224, JCM 4137, JCM 4559, NBRC 13108, NRRL B-3353, NRRL-ISP 5224, S. yokosukanensis, Streptomyces yokosukensis
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.