Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KUN04383.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)    
Predicted Functional Partners:
KUN04384.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.976
KUN00620.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.902
KUN04380.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.731
KUN04381.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.731
KUN04386.1
Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.702
KUN04382.1
Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.698
KUN06612.1
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.548
AQI95_44285
Chitinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
     
  0.544
KUN07529.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.531
pfp
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
       0.526
Your Current Organism:
Streptomyces yokosukanensis
NCBI taxonomy Id: 67386
Other names: ATCC 25520, BCRC 11875, CBS 662.69, CCRC 11875, CCRC:11875, DSM 40224, IFO 13108, ISP 5224, JCM 4137, JCM 4559, NBRC 13108, NRRL B-3353, NRRL-ISP 5224, S. yokosukanensis, Streptomyces yokosukensis
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