STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiHThiamine biosynthesis protein ThiH; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)    
Predicted Functional Partners:
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 0.999
thiC
Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.983
VM_00290
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
 
  
 0.981
thiS
Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.962
VM_00295
Molybdopterin-synthase adenylyltransferase MoeB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.910
VM_19505
Anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.859
VM_16425
DNA mismatch repair protein MutT; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Nudix hydrolase family.
  
  
 0.822
VM_19180
Two-component system sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.810
VM_19510
Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.769
flgB
Flagellar basal body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.766
Your Current Organism:
Vibrio mimicus
NCBI taxonomy Id: 674
Other names: ATCC 33653, CAIM 602, CCUG 13624, CIP 101888, DSM 19130, LMG 7896, LMG:7896, NCTC 11435, V. mimicus
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