STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VM_00540Heme biosynthesis protein HemY; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)    
Predicted Functional Partners:
VM_00545
Heme biosynthesis operon protein HemX; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.979
VM_00550
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
   
 0.912
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
    0.762
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.682
lolB
Lipoprotein localization factor LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
 
     0.665
VM_00405
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.638
lpoA
Penicillin-binding protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family.
  
     0.629
VM_10365
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.624
VM_00565
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.620
VM_00590
3',5'-cyclic-nucleotide phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.589
Your Current Organism:
Vibrio mimicus
NCBI taxonomy Id: 674
Other names: ATCC 33653, CAIM 602, CCUG 13624, CIP 101888, DSM 19130, LMG 7896, LMG:7896, NCTC 11435, V. mimicus
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