| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| VM_00600 | VM_03560 | VM_00600 | VM_03560 | 2-haloalkanoic acid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.925 |
| VM_00600 | VM_03565 | VM_00600 | VM_03565 | 2-haloalkanoic acid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.902 |
| VM_00600 | VM_11775 | VM_00600 | VM_11775 | 2-haloalkanoic acid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | 0.920 |
| VM_00600 | VM_14090 | VM_00600 | VM_14090 | 2-haloalkanoic acid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD(P)H-flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
| VM_00600 | hpaC | VM_00600 | VM_07805 | 2-haloalkanoic acid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxyphenylacetate 3-monooxygenase, reductase component; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| VM_00600 | ribH | VM_00600 | VM_03575 | 2-haloalkanoic acid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.903 |
| VM_03560 | VM_00600 | VM_03560 | VM_00600 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 2-haloalkanoic acid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.925 |
| VM_03560 | VM_03565 | VM_03560 | VM_03565 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| VM_03560 | VM_11775 | VM_03560 | VM_11775 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | 0.639 |
| VM_03560 | nrdR | VM_03560 | VM_03555 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.932 |
| VM_03560 | ribA | VM_03560 | VM_08515 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.998 |
| VM_03560 | ribB | VM_03560 | VM_03570 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
| VM_03560 | ribB-2 | VM_03560 | VM_19310 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.989 |
| VM_03560 | ribH | VM_03560 | VM_03575 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.995 |
| VM_03565 | VM_00600 | VM_03565 | VM_00600 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-haloalkanoic acid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.902 |
| VM_03565 | VM_03560 | VM_03565 | VM_03560 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| VM_03565 | VM_11775 | VM_03565 | VM_11775 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | 0.944 |
| VM_03565 | VM_14090 | VM_03565 | VM_14090 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD(P)H-flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
| VM_03565 | hpaC | VM_03565 | VM_07805 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxyphenylacetate 3-monooxygenase, reductase component; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.905 |
| VM_03565 | nrdR | VM_03565 | VM_03555 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.881 |