Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VM_04110Hypothetical protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. (484 aa)    
Predicted Functional Partners:
arsC
Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.856
VM_04095
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.839
VM_04100
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.829
VM_04115
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family.
       0.751
VM_04120
AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.751
VM_13940
Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.707
VM_02420
Zn-dependent protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.666
surA
Peptidylprolyl isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
 
  
 0.613
VM_02800
Outer membrane channel protein TolC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.590
VM_00120
Thiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.568
Your Current Organism:
Vibrio mimicus
NCBI taxonomy Id: 674
Other names: ATCC 33653, CAIM 602, CCUG 13624, CIP 101888, DSM 19130, LMG 7896, LMG:7896, NCTC 11435, V. mimicus
Server load: low (16%) [HD]