STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purRDNA transformation protein; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. (336 aa)    
Predicted Functional Partners:
VM_03075
Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.655
VM_03085
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.655
VM_15635
Bifunctional PTS fructose transporter subunit IIA/HPr protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.528
VM_10305
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.519
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
   0.489
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.463
VM_05940
PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.461
torD
Molecular chaperone TorD; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; Belongs to the TorD/DmsD family. TorD subfamily.
       0.456
VM_06350
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.435
VM_02270
Phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.427
Your Current Organism:
Vibrio mimicus
NCBI taxonomy Id: 674
Other names: ATCC 33653, CAIM 602, CCUG 13624, CIP 101888, DSM 19130, LMG 7896, LMG:7896, NCTC 11435, V. mimicus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.