STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VM_06635Fe-S oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)    
Predicted Functional Partners:
VM_08605
Ribonucleotide-diphosphate reductase subunit beta; B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.662
VM_08600
Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
     0.634
VM_06630
Heat-shock protein HslJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.577
VM_08610
(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.567
VM_18370
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.524
VM_06620
Thiamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.470
VM_09360
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.453
VM_20265
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.451
VM_02630
Anti-sigma E factor; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degradi [...]
  
     0.430
VM_07605
Universal stress protein UspE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.430
Your Current Organism:
Vibrio mimicus
NCBI taxonomy Id: 674
Other names: ATCC 33653, CAIM 602, CCUG 13624, CIP 101888, DSM 19130, LMG 7896, LMG:7896, NCTC 11435, V. mimicus
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