Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VM_07210Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)    
Predicted Functional Partners:
VM_07235
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.967
VM_07215
Flagellar motor protein MotA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.966
VM_07230
Energy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
   
 0.965
VM_07220
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.964
VM_07225
Biopolymer transporter ExbD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.959
VM_07205
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
VM_16830
Chitinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.758
VM_18925
Chitinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.758
VM_07240
DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.723
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.722
Your Current Organism:
Vibrio mimicus
NCBI taxonomy Id: 674
Other names: ATCC 33653, CAIM 602, CCUG 13624, CIP 101888, DSM 19130, LMG 7896, LMG:7896, NCTC 11435, V. mimicus
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