node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VM_10610 | VM_10620 | VM_10610 | VM_10620 | D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.540 |
VM_10610 | metN | VM_10610 | VM_10615 | D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.540 |
VM_10610 | metQ | VM_10610 | VM_10625 | D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DL-methionine transporter substrate-binding subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nlpA lipoprotein family. | 0.486 |
VM_10610 | treR | VM_10610 | VM_10605 | D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Trehalose operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.631 |
VM_10620 | VM_10610 | VM_10620 | VM_10610 | Methionine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.540 |
VM_10620 | metF | VM_10620 | VM_01540 | Methionine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. | 0.510 |
VM_10620 | metN | VM_10620 | VM_10615 | Methionine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.999 |
VM_10620 | metQ | VM_10620 | VM_10625 | Methionine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DL-methionine transporter substrate-binding subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nlpA lipoprotein family. | 0.999 |
VM_10620 | treR | VM_10620 | VM_10605 | Methionine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Trehalose operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.449 |
VM_13580 | VM_20250 | VM_13580 | VM_20250 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.949 |
VM_13580 | metF | VM_13580 | VM_01540 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. | 0.996 |
VM_13580 | metK | VM_13580 | VM_13005 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.948 |
VM_13580 | metN | VM_13580 | VM_10615 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.437 |
VM_13580 | metQ | VM_13580 | VM_10625 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | DL-methionine transporter substrate-binding subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nlpA lipoprotein family. | 0.482 |
VM_15550 | metQ | VM_15550 | VM_10625 | Sulfate transporter subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | DL-methionine transporter substrate-binding subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nlpA lipoprotein family. | 0.443 |
VM_20250 | VM_13580 | VM_20250 | VM_13580 | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.949 |
VM_20250 | metQ | VM_20250 | VM_10625 | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | DL-methionine transporter substrate-binding subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nlpA lipoprotein family. | 0.759 |
metF | VM_10620 | VM_01540 | VM_10620 | Methylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. | Methionine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.510 |
metF | VM_13580 | VM_01540 | VM_13580 | Methylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.996 |
metF | metK | VM_01540 | VM_13005 | Methylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.823 |