| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| VM_02590 | VM_10880 | VM_02590 | VM_10880 | FAD-dependent 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.563 |
| VM_02590 | bioC | VM_02590 | VM_09290 | FAD-dependent 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malonyl-[acyl-carrier protein] O-methyltransferase BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.443 |
| VM_02590 | sspA | VM_02590 | VM_12295 | FAD-dependent 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Stringent starvation protein A; Transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.515 |
| VM_02590 | ubiA | VM_02590 | VM_00450 | FAD-dependent 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.739 |
| VM_02590 | ubiB | VM_02590 | VM_00410 | FAD-dependent 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ubiquinone biosynthesis regulatory protein kinase UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.597 |
| VM_02590 | ubiG | VM_02590 | VM_08595 | FAD-dependent 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional 3-demethylubiquinol 3-O-methyltransferase/2-polyprenyl-6-hydroxyphenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.978 |
| VM_10875 | VM_10880 | VM_10875 | VM_10880 | RnfH family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0125 (RnfH) family. | Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.910 |
| VM_10875 | smpB | VM_10875 | VM_10885 | RnfH family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0125 (RnfH) family. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.559 |
| VM_10880 | VM_02590 | VM_10880 | VM_02590 | Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | FAD-dependent 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.563 |
| VM_10880 | VM_10875 | VM_10880 | VM_10875 | Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | RnfH family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0125 (RnfH) family. | 0.910 |
| VM_10880 | bioC | VM_10880 | VM_09290 | Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malonyl-[acyl-carrier protein] O-methyltransferase BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.451 |
| VM_10880 | dnaQ | VM_10880 | VM_03735 | Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.429 |
| VM_10880 | smpB | VM_10880 | VM_10885 | Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.567 |
| VM_10880 | sspA | VM_10880 | VM_12295 | Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Stringent starvation protein A; Transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.495 |
| VM_10880 | ubiA | VM_10880 | VM_00450 | Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.548 |
| VM_10880 | ubiB | VM_10880 | VM_00410 | Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ubiquinone biosynthesis regulatory protein kinase UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.527 |
| VM_10880 | ubiF | VM_10880 | VM_10320 | Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.462 |
| VM_10880 | ubiG | VM_10880 | VM_08595 | Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional 3-demethylubiquinol 3-O-methyltransferase/2-polyprenyl-6-hydroxyphenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.596 |
| bioC | VM_02590 | VM_09290 | VM_02590 | Malonyl-[acyl-carrier protein] O-methyltransferase BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | FAD-dependent 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.443 |
| bioC | VM_10880 | VM_09290 | VM_10880 | Malonyl-[acyl-carrier protein] O-methyltransferase BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.451 |