Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pheAChorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)    
Predicted Functional Partners:
tyrA
Bifunctional chorismate mutase/prephenate dehydrogenase; Catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.994
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.981
hisC
Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
 
 0.968
VM_08980
Anthranilate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.950
VM_08985
Anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.946
VM_16090
Salicylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.945
VM_08365
Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.936
VM_15610
Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.936
menF
Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.
 
 
 0.932
VM_20470
Phenylalanine-4-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.926
Your Current Organism:
Vibrio mimicus
NCBI taxonomy Id: 674
Other names: ATCC 33653, CAIM 602, CCUG 13624, CIP 101888, DSM 19130, LMG 7896, LMG:7896, NCTC 11435, V. mimicus
Server load: low (24%) [HD]