STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VM_11700Pilus assembly protein PilZ; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. (122 aa)    
Predicted Functional Partners:
VM_04640
Chemotaxis protein CheW; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.727
VM_03870
Chemotaxis protein CheR; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.721
VM_19155
Chemotaxis protein CheR; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
   
   0.721
VM_11695
Energy-dependent translational throttle protein EttA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.713
VM_13470
MSHA biogenesis protein MshO; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.680
VM_13530
MSHA biogenesis protein MshJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.666
VM_11690
Lytic murein transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.614
VM_07475
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.606
trpR
Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.
       0.602
VM_00465
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
    0.599
Your Current Organism:
Vibrio mimicus
NCBI taxonomy Id: 674
Other names: ATCC 33653, CAIM 602, CCUG 13624, CIP 101888, DSM 19130, LMG 7896, LMG:7896, NCTC 11435, V. mimicus
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