node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VM_06465 | metK | VM_06465 | VM_13005 | NAD(P)-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.809 |
VM_07450 | VM_08365 | VM_07450 | VM_08365 | Free methionine-(R)-sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.905 |
VM_07450 | VM_13580 | VM_07450 | VM_13580 | Free methionine-(R)-sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.900 |
VM_07450 | VM_20270 | VM_07450 | VM_20270 | Free methionine-(R)-sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
VM_07450 | metE | VM_07450 | VM_06425 | Free methionine-(R)-sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.900 |
VM_07450 | metK | VM_07450 | VM_13005 | Free methionine-(R)-sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.900 |
VM_08365 | VM_07450 | VM_08365 | VM_07450 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Free methionine-(R)-sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.905 |
VM_08365 | VM_13580 | VM_08365 | VM_13580 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.916 |
VM_08365 | VM_20270 | VM_08365 | VM_20270 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
VM_08365 | metE | VM_08365 | VM_06425 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.903 |
VM_08365 | metK | VM_08365 | VM_13005 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.905 |
VM_13580 | VM_07450 | VM_13580 | VM_07450 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Free methionine-(R)-sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
VM_13580 | VM_08365 | VM_13580 | VM_08365 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.916 |
VM_13580 | VM_20270 | VM_13580 | VM_20270 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.971 |
VM_13580 | guaA | VM_13580 | VM_11340 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.500 |
VM_13580 | metE | VM_13580 | VM_06425 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.971 |
VM_13580 | metF | VM_13580 | VM_01540 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. | 0.996 |
VM_13580 | metK | VM_13580 | VM_13005 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.948 |
VM_20270 | VM_07450 | VM_20270 | VM_07450 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Free methionine-(R)-sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
VM_20270 | VM_08365 | VM_20270 | VM_08365 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |