| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| VM_00010 | VM_05775 | VM_00010 | VM_05775 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
| VM_00010 | VM_13110 | VM_00010 | VM_13110 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.638 |
| VM_05775 | VM_00010 | VM_05775 | VM_00010 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.921 |
| VM_05775 | VM_13110 | VM_05775 | VM_13110 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.907 |
| VM_05775 | birA | VM_05775 | VM_14040 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.864 |
| VM_13090 | VM_13110 | VM_13090 | VM_13110 | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.436 |
| VM_13110 | VM_00010 | VM_13110 | VM_00010 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.638 |
| VM_13110 | VM_05775 | VM_13110 | VM_05775 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.907 |
| VM_13110 | VM_13090 | VM_13110 | VM_13090 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.436 |
| VM_13110 | VM_13115 | VM_13110 | VM_13115 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Oxidative damage protection protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.787 |
| VM_13110 | VM_13120 | VM_13110 | VM_13120 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Lytic murein transglycosylase; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.569 |
| VM_13110 | birA | VM_13110 | VM_14040 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.522 |
| VM_13110 | msrB-3 | VM_13110 | VM_16330 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.436 |
| VM_13110 | sfsA | VM_13110 | VM_12200 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Sugar fermentation stimulation protein SfsA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SfsA family. | 0.931 |
| VM_13110 | trmB | VM_13110 | VM_13105 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | tRNA (guanosine(46)-N7)-methyltransferase TrmB; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.559 |
| VM_13110 | trpF | VM_13110 | VM_08995 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. | 0.446 |
| VM_13115 | VM_13110 | VM_13115 | VM_13110 | Oxidative damage protection protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.787 |
| VM_13115 | VM_13120 | VM_13115 | VM_13120 | Oxidative damage protection protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Lytic murein transglycosylase; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.626 |
| VM_13115 | trmB | VM_13115 | VM_13105 | Oxidative damage protection protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | tRNA (guanosine(46)-N7)-methyltransferase TrmB; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.512 |
| VM_13120 | VM_13110 | VM_13120 | VM_13110 | Lytic murein transglycosylase; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.569 |