| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| VM_13815 | VM_13850 | VM_13815 | VM_13850 | DUF2065 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.460 |
| VM_13815 | hflC | VM_13815 | VM_13820 | DUF2065 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | HflC protein; HflC and HflK could regulate a protease. | 0.652 |
| VM_13815 | hflK | VM_13815 | VM_13825 | DUF2065 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | HflK protein; HflC and HflK could encode or regulate a protease. | 0.705 |
| VM_13815 | hflX | VM_13815 | VM_13830 | DUF2065 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.577 |
| VM_13815 | hfq | VM_13815 | VM_13835 | DUF2065 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.502 |
| VM_13850 | VM_13815 | VM_13850 | VM_13815 | N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DUF2065 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.460 |
| VM_13850 | hflC | VM_13850 | VM_13820 | N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | HflC protein; HflC and HflK could regulate a protease. | 0.495 |
| VM_13850 | hflK | VM_13850 | VM_13825 | N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | HflK protein; HflC and HflK could encode or regulate a protease. | 0.502 |
| VM_13850 | hflX | VM_13850 | VM_13830 | N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.613 |
| VM_13850 | hfq | VM_13850 | VM_13835 | N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.622 |
| VM_13850 | miaA | VM_13850 | VM_13840 | N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.897 |
| hflB | hflC | VM_12015 | VM_13820 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | HflC protein; HflC and HflK could regulate a protease. | 0.861 |
| hflB | hflK | VM_12015 | VM_13825 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | HflK protein; HflC and HflK could encode or regulate a protease. | 0.892 |
| hflB | hflX | VM_12015 | VM_13830 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.472 |
| hflB | hfq | VM_12015 | VM_13835 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.471 |
| hflB | miaA | VM_12015 | VM_13840 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.491 |
| hflB | tig | VM_12015 | VM_05310 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Hypothetical protein; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.533 |
| hflB | yidC | VM_12015 | VM_15050 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.556 |
| hflC | VM_13815 | VM_13820 | VM_13815 | HflC protein; HflC and HflK could regulate a protease. | DUF2065 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.652 |
| hflC | VM_13850 | VM_13820 | VM_13850 | HflC protein; HflC and HflK could regulate a protease. | N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.495 |