| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| VM_00010 | VM_18350 | VM_00010 | VM_18350 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.495 |
| VM_00360 | VM_07605 | VM_00360 | VM_07605 | Universal stress global response regulator UspA; Involved in resistance to DNA-damaging agents; Derived by automated computational analysis using gene prediction method: Protein Homology. | Universal stress protein UspE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.663 |
| VM_00360 | VM_18350 | VM_00360 | VM_18350 | Universal stress global response regulator UspA; Involved in resistance to DNA-damaging agents; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.439 |
| VM_06585 | VM_18350 | VM_06585 | VM_18350 | DNA-3-methyladenine glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.770 |
| VM_06585 | VM_18355 | VM_06585 | VM_18355 | DNA-3-methyladenine glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.465 |
| VM_07605 | VM_00360 | VM_07605 | VM_00360 | Universal stress protein UspE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Universal stress global response regulator UspA; Involved in resistance to DNA-damaging agents; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.663 |
| VM_07605 | VM_18350 | VM_07605 | VM_18350 | Universal stress protein UspE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.439 |
| VM_07835 | VM_18350 | VM_07835 | VM_18350 | Universal stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.439 |
| VM_18345 | VM_18350 | VM_18345 | VM_18350 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.849 |
| VM_18345 | VM_18355 | VM_18345 | VM_18355 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.849 |
| VM_18345 | VM_18360 | VM_18345 | VM_18360 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DoxD-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.442 |
| VM_18350 | VM_00010 | VM_18350 | VM_00010 | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.495 |
| VM_18350 | VM_00360 | VM_18350 | VM_00360 | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Universal stress global response regulator UspA; Involved in resistance to DNA-damaging agents; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.439 |
| VM_18350 | VM_06585 | VM_18350 | VM_06585 | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | DNA-3-methyladenine glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.770 |
| VM_18350 | VM_07605 | VM_18350 | VM_07605 | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Universal stress protein UspE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.439 |
| VM_18350 | VM_07835 | VM_18350 | VM_07835 | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Universal stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.439 |
| VM_18350 | VM_18345 | VM_18350 | VM_18345 | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.849 |
| VM_18350 | VM_18355 | VM_18350 | VM_18355 | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |
| VM_18350 | VM_18360 | VM_18350 | VM_18360 | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | DoxD-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.478 |
| VM_18350 | lpxB | VM_18350 | VM_03675 | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.638 |