STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (342 aa)    
Predicted Functional Partners:
pyrD
Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 
 0.988
pyrB
Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
 
 0.979
pyrI
Aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
   
 
  0.946
carB
Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family.
   
  
 0.706
purM
Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.654
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
  
 0.636
VM_20070
Flavodoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.632
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
      
 0.615
carA
Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family.
   
  
 0.606
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
      
 0.568
Your Current Organism:
Vibrio mimicus
NCBI taxonomy Id: 674
Other names: ATCC 33653, CAIM 602, CCUG 13624, CIP 101888, DSM 19130, LMG 7896, LMG:7896, NCTC 11435, V. mimicus
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