node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMN39421.1 | AMN40204.1 | RHPLAN_09590 | RHPLAN_17530 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | Thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase; Belongs to the TPP enzyme family. | 0.700 |
AMN39421.1 | AMN41619.1 | RHPLAN_09590 | RHPLAN_31840 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.781 |
AMN39421.1 | AMN42138.1 | RHPLAN_09590 | RHPLAN_37060 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | Threonine dehydratase. | 0.745 |
AMN39421.1 | AMN43379.1 | RHPLAN_09590 | RHPLAN_49550 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | Threonine dehydratase. | 0.745 |
AMN39421.1 | AMN44154.1 | RHPLAN_09590 | RHPLAN_57400 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | Acetolactate synthase small subunit. | 0.901 |
AMN39421.1 | ilvC | RHPLAN_09590 | RHPLAN_57350 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.942 |
AMN39421.1 | leuB | RHPLAN_09590 | RHPLAN_04490 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.824 |
AMN40204.1 | AMN39421.1 | RHPLAN_17530 | RHPLAN_09590 | Thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase; Belongs to the TPP enzyme family. | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | 0.700 |
AMN40204.1 | AMN41491.1 | RHPLAN_17530 | RHPLAN_30550 | Thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase; Belongs to the TPP enzyme family. | Acetolactate synthase catalytic subunit; Belongs to the TPP enzyme family. | 0.708 |
AMN40204.1 | AMN41619.1 | RHPLAN_17530 | RHPLAN_31840 | Thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase; Belongs to the TPP enzyme family. | 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.875 |
AMN40204.1 | AMN42392.1 | RHPLAN_17530 | RHPLAN_39600 | Thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase; Belongs to the TPP enzyme family. | Thiamine pyrophosphate TPP-binding domain-containing protein; Belongs to the TPP enzyme family. | 0.716 |
AMN40204.1 | AMN44154.1 | RHPLAN_17530 | RHPLAN_57400 | Thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase; Belongs to the TPP enzyme family. | Acetolactate synthase small subunit. | 0.918 |
AMN40204.1 | AMN44155.1 | RHPLAN_17530 | RHPLAN_57410 | Thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase; Belongs to the TPP enzyme family. | Acetolactate synthase large subunit. | 0.697 |
AMN40204.1 | ilvC | RHPLAN_17530 | RHPLAN_57350 | Thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.646 |
AMN41491.1 | AMN40204.1 | RHPLAN_30550 | RHPLAN_17530 | Acetolactate synthase catalytic subunit; Belongs to the TPP enzyme family. | Thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase; Belongs to the TPP enzyme family. | 0.708 |
AMN41491.1 | AMN41619.1 | RHPLAN_30550 | RHPLAN_31840 | Acetolactate synthase catalytic subunit; Belongs to the TPP enzyme family. | 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.796 |
AMN41491.1 | AMN42138.1 | RHPLAN_30550 | RHPLAN_37060 | Acetolactate synthase catalytic subunit; Belongs to the TPP enzyme family. | Threonine dehydratase. | 0.745 |
AMN41491.1 | AMN43379.1 | RHPLAN_30550 | RHPLAN_49550 | Acetolactate synthase catalytic subunit; Belongs to the TPP enzyme family. | Threonine dehydratase. | 0.745 |
AMN41491.1 | AMN44154.1 | RHPLAN_30550 | RHPLAN_57400 | Acetolactate synthase catalytic subunit; Belongs to the TPP enzyme family. | Acetolactate synthase small subunit. | 0.914 |
AMN41491.1 | ilvC | RHPLAN_30550 | RHPLAN_57350 | Acetolactate synthase catalytic subunit; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.946 |