STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M2YLZ9_DOTSNSuccinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (349 aa)    
Predicted Functional Partners:
lsc2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
N1PTJ2_DOTSN
Transket_pyr domain-containing protein.
  
 0.987
M2WK03_DOTSN
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 0.978
N1PE31_DOTSN
Citrate_bind domain-containing protein.
  
 0.978
N1PH30_DOTSN
CoA_binding domain-containing protein.
  
0.978
M2YPZ6_DOTSN
Uncharacterized protein.
  
 
 0.968
N1PC16_DOTSN
Lipoyl-binding domain-containing protein.
  
 0.967
N1PWN8_DOTSN
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.947
N1Q2T9_DOTSN
Uncharacterized protein.
  
 0.947
N1PX51_DOTSN
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit.
   
 
 0.934
Your Current Organism:
Dothistroma septosporum
NCBI taxonomy Id: 675120
Other names: D. septosporum NZE10, Dothistroma septosporum NZE10, Mycosphaerella pini NZE10
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