STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N1PHQ6_DOTSNPKS_AT domain-containing protein; Belongs to the fungal fatty acid synthetase subunit beta family. (2093 aa)    
Predicted Functional Partners:
N1PGA9_DOTSN
Carrier domain-containing protein; Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.
 
  
  0.991
hexA
3-oxoacyl-[acyl-carrier-protein] reductase; Fatty acid synthase alpha subunit; part of the fragmented gene cluster that mediates the biosynthesis of dothistromin (DOTH), a polyketide toxin very similar in structure to the aflatoxin precursor, versicolorin B. The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits hexA and hexB, as well as the polyketide synthase pksA. PksA combines a hexanoyl starter unit and 7 malonyl-CoA extender units to synthesize the precursor NOR (By similarity). The hexanoyl starter unit [...]
 
  
  0.986
N1PTV3_DOTSN
Uncharacterized protein.
   
 0.910
ksd2
3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
     
 0.803
N1PV07_DOTSN
AMP-binding domain-containing protein.
   
 0.803
N1PH30_DOTSN
CoA_binding domain-containing protein.
    
 0.800
N1PE31_DOTSN
Citrate_bind domain-containing protein.
    
 0.795
N1PWN8_DOTSN
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
  0.789
N1PYE1_DOTSN
Uncharacterized protein.
    
 0.786
mcp1
Malonyl-CoA-acyl carrier protein transacylase-like protein.
    
 0.781
Your Current Organism:
Dothistroma septosporum
NCBI taxonomy Id: 675120
Other names: D. septosporum NZE10, Dothistroma septosporum NZE10, Mycosphaerella pini NZE10
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.