STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htpGUnannotated protein; Molecular chaperone. Has ATPase activity. (639 aa)    
Predicted Functional Partners:
dnaJ
Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]
 
 0.985
dnaK
Unannotated protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.978
EQU24_04730
Unannotated protein.
   
 0.975
EQU24_04725
Unannotated protein; Belongs to the heat shock protein 70 family.
   
 0.975
EQU24_03380
Unannotated protein; Belongs to the heat shock protein 70 family.
   
 0.975
EQU24_18570
Unannotated protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.969
EQU24_06990
Unannotated protein.
  
 0.963
EQU24_03390
Unannotated protein.
  
 0.963
EQU24_15860
Unannotated protein.
   
 0.957
EQU24_06440
Unannotated protein.
    
 0.909
Your Current Organism:
Methylomicrobium buryatense
NCBI taxonomy Id: 675511
Other names: M. buryatense 5G, Methylomicrobium buryatense 5G, Methylomicrobium buryatense str. 5G, Methylomicrobium buryatense strain 5G
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.