STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Psed_1547Pyruvate carboxylase; KEGG: rop:ROP_29690 putative carboxyltransferase; PFAM: Carboxylase, conserved domain; Pyruvate carboxyltransferase. (491 aa)    
Predicted Functional Partners:
Psed_1546
Biotin carboxylase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; KEGG: rop:ROP_29700 acetyl-CoA carboxylase biotin carboxylase subunit; SMART: Biotin carboxylase, C-terminal.
  
 
 0.976
Psed_1552
KEGG: rop:ROP_29720 pyruvate phosphate dikinase; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile domain.
    
 0.943
Psed_5549
TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: ami:Amir_6664 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal.
  
 
 0.938
Psed_4769
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
  
0.932
Psed_2869
TIGRFAM: Pyruvate kinase; KEGG: ami:Amir_5687 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; Belongs to the pyruvate kinase family.
  
 
 0.920
Psed_3032
Pyruvate carboxylase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; KEGG: rop:ROP_29700 acetyl-CoA carboxylase biotin carboxylase subunit; SMART: Biotin carboxylase, C-terminal.
  
 
 0.918
Psed_5550
KEGG: rha:RHA1_ro02389 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
  
 
 0.918
Psed_2085
HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: nml:Namu_2341 lactate/malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal.
    
 0.916
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
    
 0.916
Psed_3034
KEGG: sti:Sthe_2821 pyruvate carboxylase; PFAM: Carboxylase, conserved domain; Pyruvate carboxyltransferase.
  
  
 
0.916
Your Current Organism:
Pseudonocardia dioxanivorans
NCBI taxonomy Id: 675635
Other names: P. dioxanivorans CB1190, Pseudonocardia dioxanivorans CB1190, Pseudonocardia dioxanivorans DSM 44775, Pseudonocardia dioxanivorans str. CB1190, Pseudonocardia dioxanivorans strain CB1190
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