STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (302 aa)    
Predicted Functional Partners:
Psed_1664
PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; KEGG: amd:AMED_7795 homoserine dehydrogenase.
  
 0.999
Psed_1665
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
 
 0.998
Psed_2011
TIGRFAM: Threonine synthase; KEGG: ami:Amir_1205 threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit.
 
 
 0.980
Psed_3326
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.895
Psed_2107
Methionine synthase; KEGG: tro:trd_1049 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; PFAM: Homocysteine S-methyltransferase; Methylenetetrahydrofolate reductase.
    
 0.891
Psed_2549
L-serine dehydratase 1; TIGRFAM: Iron-sulphur-dependent L-serine dehydratase single chain form; KEGG: rop:ROP_15050 L-serine dehydratase; PFAM: Serine dehydratase-like, alpha subunit; Serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
 
 
 0.875
purM
TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: sen:SACE_7124 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein.
    
 0.867
Psed_2102
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; KEGG: iag:Igag_0649 methionine synthase (B12-independent); PFAM: Methionine synthase, vitamin-B12 independent.
  
 
 0.858
Psed_4561
TIGRFAM: Branched-chain amino acid aminotransferase II; KEGG: nml:Namu_1869 branched-chain amino acid aminotransferase; PFAM: Aminotransferase, class IV.
  
 
 0.855
Psed_2853
PFAM: Methionine synthase, vitamin-B12 independent; KEGG: bbt:BBta_2188 methionine synthase (B12-independent).
  
 
 0.853
Your Current Organism:
Pseudonocardia dioxanivorans
NCBI taxonomy Id: 675635
Other names: P. dioxanivorans CB1190, Pseudonocardia dioxanivorans CB1190, Pseudonocardia dioxanivorans DSM 44775, Pseudonocardia dioxanivorans str. CB1190, Pseudonocardia dioxanivorans strain CB1190
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