STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (200 aa)    
Predicted Functional Partners:
nadE
NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.980
Psed_1505
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
 
 0.962
Psed_2847
TIGRFAM: Nicotinate-nucleotide pyrophosphorylase; KEGG: ami:Amir_5728 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal; Belongs to the NadC/ModD family.
    
 0.958
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
 
 0.949
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
  
 0.939
Psed_2146
KEGG: hch:HCH_06992 putative nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; Belongs to the NAPRTase family.
  
 
 0.918
Psed_2158
KEGG: hch:HCH_06992 putative nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; Belongs to the NAPRTase family.
  
 
 0.918
Psed_2182
KEGG: hch:HCH_06992 putative nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; Belongs to the NAPRTase family.
  
 
 0.918
Psed_1112
NAD(+) diphosphatase; KEGG: fal:FRAAL0398 NADH pyrophosphatase; PFAM: NUDIX hydrolase domain; Zinc ribbon, NADH pyrophosphatase; NADH pyrophosphatase-like, N-terminal.
     
 0.907
Psed_5404
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
    
 0.907
Your Current Organism:
Pseudonocardia dioxanivorans
NCBI taxonomy Id: 675635
Other names: P. dioxanivorans CB1190, Pseudonocardia dioxanivorans CB1190, Pseudonocardia dioxanivorans DSM 44775, Pseudonocardia dioxanivorans str. CB1190, Pseudonocardia dioxanivorans strain CB1190
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