Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Psed_2115PFAM: Protein of unknown function DUF349; KEGG: ami:Amir_1442 protein of unknown function DUF349. (700 aa)    
Predicted Functional Partners:
Psed_3055
KEGG: rop:ROP_68120 hypothetical protein.
  
     0.756
rbpA
Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
     0.754
Psed_4572
KEGG: rop:ROP_08820 hypothetical membrane protein.
  
     0.709
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
     0.693
Psed_2012
DNA polymerase III, delta subunit; KEGG: svi:Svir_12630 hypothetical protein; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta.
 
   
 0.689
Psed_3162
Regulatory protein MerR; KEGG: req:REQ_24440 MerR family transcriptional regulator; manually curated; SMART: HTH transcriptional regulator, MerR.
 
     0.670
Psed_1114
UvrD/REP helicase; KEGG: amd:AMED_1233 ATP-dependent DNA helicase; PFAM: DNA helicase, UvrD/REP type; Helicase/RNase D C-terminal, HRDC domain; SMART: Helicase/RNase D C-terminal, HRDC domain.
  
 
 0.659
Psed_3388
KEGG: sen:SACE_2187 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.
 
 
 
 0.631
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.628
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
   
   0.624
Your Current Organism:
Pseudonocardia dioxanivorans
NCBI taxonomy Id: 675635
Other names: P. dioxanivorans CB1190, Pseudonocardia dioxanivorans CB1190, Pseudonocardia dioxanivorans DSM 44775, Pseudonocardia dioxanivorans str. CB1190, Pseudonocardia dioxanivorans strain CB1190
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