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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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fabH3-oxoacyl-(acyl-carrier-protein) synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (329 aa)    
Predicted Functional Partners:
Psed_2137
(Acyl-carrier-protein) S-malonyltransferase; PFAM: Acyl transferase; KEGG: rha:RHA1_ro01199 [acyl-carrier protein] S-malonyltransferase; SMART: Polyketide synthase, acyl transferase domain.
 
 
 0.999
Psed_2134
Beta-ketoacyl-acyl-carrier-protein synthase I; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.998
Psed_0508
Beta-ketoacyl-acyl-carrier-protein synthase II; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; KEGG: nca:Noca_4118 beta-ketoacyl synthase; SMART: Polyketide synthase, beta-ketoacyl synthase domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.995
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
 
 
 0.987
Psed_1545
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.977
Psed_3033
Biotin/lipoyl attachment domain-containing protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.970
Psed_1546
Biotin carboxylase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; KEGG: rop:ROP_29700 acetyl-CoA carboxylase biotin carboxylase subunit; SMART: Biotin carboxylase, C-terminal.
 
 
 0.965
Psed_3032
Pyruvate carboxylase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; KEGG: rop:ROP_29700 acetyl-CoA carboxylase biotin carboxylase subunit; SMART: Biotin carboxylase, C-terminal.
 
 
 0.965
Psed_5269
Biotin carboxylase., Pyruvate carboxylase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; Biotin/lipoyl attachment; KEGG: mjl:Mjls_1325 carbamoyl-phosphate synthase L chain, ATP-binding; SMART: Biotin carboxylase, C-terminal.
 
 
 0.963
Psed_5275
KEGG: ami:Amir_6396 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; Biotin/lipoyl attachment; SMART: Biotin carboxylase, C-terminal.
 
 
 0.963
Your Current Organism:
Pseudonocardia dioxanivorans
NCBI taxonomy Id: 675635
Other names: P. dioxanivorans CB1190, Pseudonocardia dioxanivorans CB1190, Pseudonocardia dioxanivorans DSM 44775, Pseudonocardia dioxanivorans str. CB1190, Pseudonocardia dioxanivorans strain CB1190
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