node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Psed_1820 | Psed_1821 | Psed_1820 | Psed_1821 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: ami:Amir_6021 acetolactate synthase 1 catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. | KEGG: svi:Svir_08880 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 0.999 |
Psed_1820 | Psed_4561 | Psed_1820 | Psed_4561 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: ami:Amir_6021 acetolactate synthase 1 catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. | TIGRFAM: Branched-chain amino acid aminotransferase II; KEGG: nml:Namu_1869 branched-chain amino acid aminotransferase; PFAM: Aminotransferase, class IV. | 0.583 |
Psed_1820 | ilvC | Psed_1820 | Psed_1822 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: ami:Amir_6021 acetolactate synthase 1 catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.996 |
Psed_1820 | ilvD | Psed_1820 | Psed_1818 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: ami:Amir_6021 acetolactate synthase 1 catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. | PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: amd:AMED_1683 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.917 |
Psed_1820 | ilvD-2 | Psed_1820 | Psed_3071 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: ami:Amir_6021 acetolactate synthase 1 catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. | PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: sen:SACE_1280 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.887 |
Psed_1820 | ilvD-3 | Psed_1820 | Psed_4169 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: ami:Amir_6021 acetolactate synthase 1 catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. | HAMAP: Dihydroxy-acid dehydratase; KEGG: rxy:Rxyl_1326 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.886 |
Psed_1820 | leuA | Psed_1820 | Psed_0359 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: ami:Amir_6021 acetolactate synthase 1 catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.931 |
Psed_1820 | leuC | Psed_1820 | Psed_1832 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: ami:Amir_6021 acetolactate synthase 1 catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.816 |
Psed_1820 | leuD | Psed_1820 | Psed_1833 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: ami:Amir_6021 acetolactate synthase 1 catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.827 |
Psed_1821 | Psed_1820 | Psed_1821 | Psed_1820 | KEGG: svi:Svir_08880 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: ami:Amir_6021 acetolactate synthase 1 catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. | 0.999 |
Psed_1821 | Psed_4561 | Psed_1821 | Psed_4561 | KEGG: svi:Svir_08880 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | TIGRFAM: Branched-chain amino acid aminotransferase II; KEGG: nml:Namu_1869 branched-chain amino acid aminotransferase; PFAM: Aminotransferase, class IV. | 0.725 |
Psed_1821 | ilvC | Psed_1821 | Psed_1822 | KEGG: svi:Svir_08880 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |
Psed_1821 | ilvD | Psed_1821 | Psed_1818 | KEGG: svi:Svir_08880 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: amd:AMED_1683 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.920 |
Psed_1821 | ilvD-2 | Psed_1821 | Psed_3071 | KEGG: svi:Svir_08880 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: sen:SACE_1280 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.898 |
Psed_1821 | ilvD-3 | Psed_1821 | Psed_4169 | KEGG: svi:Svir_08880 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | HAMAP: Dihydroxy-acid dehydratase; KEGG: rxy:Rxyl_1326 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.906 |
Psed_1821 | leuA | Psed_1821 | Psed_0359 | KEGG: svi:Svir_08880 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.970 |
Psed_1821 | leuC | Psed_1821 | Psed_1832 | KEGG: svi:Svir_08880 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.888 |
Psed_1821 | leuD | Psed_1821 | Psed_1833 | KEGG: svi:Svir_08880 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.926 |
Psed_4561 | Psed_1820 | Psed_4561 | Psed_1820 | TIGRFAM: Branched-chain amino acid aminotransferase II; KEGG: nml:Namu_1869 branched-chain amino acid aminotransferase; PFAM: Aminotransferase, class IV. | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: ami:Amir_6021 acetolactate synthase 1 catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. | 0.583 |
Psed_4561 | Psed_1821 | Psed_4561 | Psed_1821 | TIGRFAM: Branched-chain amino acid aminotransferase II; KEGG: nml:Namu_1869 branched-chain amino acid aminotransferase; PFAM: Aminotransferase, class IV. | KEGG: svi:Svir_08880 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 0.725 |