STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
whiB-6Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (104 aa)    
Predicted Functional Partners:
Psed_4736
PFAM: Protein of unknown function DUF2469; KEGG: ami:Amir_5918 hypothetical protein.
  
     0.696
Psed_5357
Regulatory protein MerR; KEGG: ami:Amir_6541 transcriptional regulator, MerR family; PFAM: HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR.
 
     0.670
Psed_3321
KEGG: sen:SACE_2242 RecB family exonuclease.
  
     0.656
Psed_3162
Regulatory protein MerR; KEGG: req:REQ_24440 MerR family transcriptional regulator; manually curated; SMART: HTH transcriptional regulator, MerR.
  
   
 0.622
Psed_5611
KEGG: gbr:Gbro_1035 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SMART: Histidine phosphatase superfamily, clade-1.
  
     0.598
Psed_2978
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 
 0.580
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.580
Psed_5356
KEGG: req:REQ_34970 hypothetical protein.
       0.576
Psed_5154
Signal transduction histidine kinase; KEGG: sen:SACE_6427 putative two-component system sensor kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold-4; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain.
  
     0.521
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.518
Your Current Organism:
Pseudonocardia dioxanivorans
NCBI taxonomy Id: 675635
Other names: P. dioxanivorans CB1190, Pseudonocardia dioxanivorans CB1190, Pseudonocardia dioxanivorans DSM 44775, Pseudonocardia dioxanivorans str. CB1190, Pseudonocardia dioxanivorans strain CB1190
Server load: low (16%) [HD]