| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX36309.1 | EEX38592.1 | VIB_002624 | VIB_000056 | Protein BatA; Bacteroides aerotolerance operon. | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | 0.492 |
| EEX36309.1 | mnmC | VIB_002624 | VIB_000789 | Protein BatA; Bacteroides aerotolerance operon. | 5-methylaminomethyl-2-thiouridine-forming enzyme MnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.412 |
| EEX37698.1 | EEX38592.1 | VIB_001823 | VIB_000056 | Hypothetical protein. | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | 0.825 |
| EEX38428.1 | EEX38592.1 | VIB_000374 | VIB_000056 | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | 0.429 |
| EEX38428.1 | glyA | VIB_000374 | VIB_001745 | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.451 |
| EEX38428.1 | ubiB | VIB_000374 | VIB_000045 | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. | Ubiquinone biosynthesis monooxygenase UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.600 |
| EEX38592.1 | EEX36309.1 | VIB_000056 | VIB_002624 | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | Protein BatA; Bacteroides aerotolerance operon. | 0.492 |
| EEX38592.1 | EEX37698.1 | VIB_000056 | VIB_001823 | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | Hypothetical protein. | 0.825 |
| EEX38592.1 | EEX38428.1 | VIB_000056 | VIB_000374 | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. | 0.429 |
| EEX38592.1 | EEX38594.1 | VIB_000056 | VIB_000058 | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | Hypothetical protein. | 0.822 |
| EEX38592.1 | EEX38595.1 | VIB_000056 | VIB_000059 | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | Coproporphyrinogen III oxidase oxygen-independent; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.501 |
| EEX38592.1 | gcvP | VIB_000056 | VIB_002339 | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.755 |
| EEX38592.1 | glyA | VIB_000056 | VIB_001745 | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.498 |
| EEX38592.1 | mnmC | VIB_000056 | VIB_000789 | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | 5-methylaminomethyl-2-thiouridine-forming enzyme MnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.465 |
| EEX38592.1 | ubiB | VIB_000056 | VIB_000045 | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | Ubiquinone biosynthesis monooxygenase UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.461 |
| EEX38592.1 | yihI | VIB_000056 | VIB_000057 | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | Hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.826 |
| EEX38594.1 | EEX38592.1 | VIB_000058 | VIB_000056 | Hypothetical protein. | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | 0.822 |
| EEX38594.1 | EEX38595.1 | VIB_000058 | VIB_000059 | Hypothetical protein. | Coproporphyrinogen III oxidase oxygen-independent; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.496 |
| EEX38594.1 | yihI | VIB_000058 | VIB_000057 | Hypothetical protein. | Hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.939 |
| EEX38595.1 | EEX38592.1 | VIB_000059 | VIB_000056 | Coproporphyrinogen III oxidase oxygen-independent; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; COG2227. | 0.501 |