| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX36171.1 | EEX36764.1 | VIB_002485 | VIB_000870 | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | L-asparaginase. | 0.630 |
| EEX36171.1 | ddl | VIB_002485 | VIB_002180 | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.583 |
| EEX36171.1 | glsA | VIB_002485 | VIB_002082 | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutaminase; Belongs to the glutaminase family. | 0.633 |
| EEX36171.1 | murI | VIB_002485 | VIB_000098 | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.667 |
| EEX36171.1 | purL | VIB_002485 | VIB_001782 | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.811 |
| EEX36658.1 | murC | VIB_000763 | VIB_001963 | Flagellin protein FlaG. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.729 |
| EEX36658.1 | murI | VIB_000763 | VIB_000098 | Flagellin protein FlaG. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.729 |
| EEX36658.1 | purL | VIB_000763 | VIB_001782 | Flagellin protein FlaG. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.729 |
| EEX36764.1 | EEX36171.1 | VIB_000870 | VIB_002485 | L-asparaginase. | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.630 |
| EEX36764.1 | glsA | VIB_000870 | VIB_002082 | L-asparaginase. | Glutaminase; Belongs to the glutaminase family. | 0.607 |
| EEX36764.1 | guaA | VIB_000870 | VIB_001846 | L-asparaginase. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.466 |
| EEX36764.1 | murI | VIB_000870 | VIB_000098 | L-asparaginase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.615 |
| EEX36764.1 | purL | VIB_000870 | VIB_001782 | L-asparaginase. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.618 |
| EEX37948.1 | guaA | VIB_002080 | VIB_001846 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.926 |
| EEX37948.1 | murD | VIB_002080 | VIB_001966 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.611 |
| EEX37948.1 | murI | VIB_002080 | VIB_000098 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.911 |
| EEX37948.1 | purL | VIB_002080 | VIB_001782 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.535 |
| ddl | EEX36171.1 | VIB_002180 | VIB_002485 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.583 |
| ddl | murC | VIB_002180 | VIB_001963 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.994 |
| ddl | murD | VIB_002180 | VIB_001966 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.960 |