| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX38219.1 | EEX38256.1 | VIB_000593 | VIB_000201 | Putative alpha helix protein; Belongs to the UPF0307 family. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.878 |
| EEX38219.1 | obg | VIB_000593 | VIB_002097 | Putative alpha helix protein; Belongs to the UPF0307 family. | GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.794 |
| EEX38219.1 | rplC | VIB_000593 | VIB_000538 | Putative alpha helix protein; Belongs to the UPF0307 family. | LSU ribosomal protein L3p (L3e); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.804 |
| EEX38219.1 | rplF | VIB_000593 | VIB_000553 | Putative alpha helix protein; Belongs to the UPF0307 family. | LSU ribosomal protein L6p (L9e); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.791 |
| EEX38219.1 | rplM | VIB_000593 | VIB_001983 | Putative alpha helix protein; Belongs to the UPF0307 family. | LSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.794 |
| EEX38219.1 | rplR | VIB_000593 | VIB_000554 | Putative alpha helix protein; Belongs to the UPF0307 family. | LSU ribosomal protein L18p (L5e); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.791 |
| EEX38219.1 | rplT | VIB_000593 | VIB_002781 | Putative alpha helix protein; Belongs to the UPF0307 family. | LSU ribosomal protein L20p; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.791 |
| EEX38219.1 | rplU | VIB_000593 | VIB_002099 | Putative alpha helix protein; Belongs to the UPF0307 family. | LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.793 |
| EEX38219.1 | rsfS | VIB_000593 | VIB_001737 | Putative alpha helix protein; Belongs to the UPF0307 family. | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.804 |
| EEX38256.1 | EEX38219.1 | VIB_000201 | VIB_000593 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Putative alpha helix protein; Belongs to the UPF0307 family. | 0.878 |
| EEX38256.1 | mnmE | VIB_000201 | VIB_003026 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | GTPase and tRNA-U34 5-formylation enzyme TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.887 |
| EEX38256.1 | obg | VIB_000201 | VIB_002097 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.943 |
| EEX38256.1 | rplC | VIB_000201 | VIB_000538 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L3p (L3e); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.850 |
| EEX38256.1 | rplF | VIB_000201 | VIB_000553 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L6p (L9e); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.838 |
| EEX38256.1 | rplM | VIB_000201 | VIB_001983 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.847 |
| EEX38256.1 | rplR | VIB_000201 | VIB_000554 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L18p (L5e); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.882 |
| EEX38256.1 | rplT | VIB_000201 | VIB_002781 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L20p; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.848 |
| EEX38256.1 | rplU | VIB_000201 | VIB_002099 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.851 |
| EEX38256.1 | rsfS | VIB_000201 | VIB_001737 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.839 |
| mnmE | EEX38256.1 | VIB_003026 | VIB_000201 | GTPase and tRNA-U34 5-formylation enzyme TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.887 |