STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEX38428.12-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. (417 aa)    
Predicted Functional Partners:
ubiG
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 
 0.959
EEX38429.1
2-octaprenyl-6-methoxyphenol hydroxylase.
 
    
0.843
EEX35697.1
3-polyprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family.
 
  
 0.823
EEX36103.1
Flavodoxin reductases, family 1.
 
  
 0.803
EEX38430.1
Hypothetical protein; Belongs to the UPF0149 family.
     
 0.794
EEX37150.1
Sterol desaturase.
   
 0.776
EEX36824.1
NADH oxidoreductase Hcr.
     
 0.763
ubiA
4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
  
   
 0.748
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
  
 
 0.716
EEX36068.1
hydroxymethylglutaryl-CoA reductase.
  
  
 0.681
Your Current Organism:
Vibrio metschnikovii
NCBI taxonomy Id: 675813
Other names: V. metschnikovii CIP 69.14, Vibrio metschnikovii CIP 69.14, Vibrio metschnikovii str. CIP 69.14, Vibrio metschnikovii strain CIP 69.14
Server load: low (20%) [HD]