| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX38036.1 | EEX38037.1 | VIB_000405 | VIB_000406 | Ribosome-associated heat shock protein; Implicated in the recycling of the LSU (S4 paralog). | General secretion pathway protein C. | 0.647 |
| EEX38036.1 | EEX38040.1 | VIB_000405 | VIB_000409 | Ribosome-associated heat shock protein; Implicated in the recycling of the LSU (S4 paralog). | General secretion pathway protein F. | 0.621 |
| EEX38036.1 | dnaJ | VIB_000405 | VIB_001794 | Ribosome-associated heat shock protein; Implicated in the recycling of the LSU (S4 paralog). | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.684 |
| EEX38036.1 | grpE | VIB_000405 | VIB_001796 | Ribosome-associated heat shock protein; Implicated in the recycling of the LSU (S4 paralog). | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.684 |
| EEX38036.1 | hslO | VIB_000405 | VIB_000404 | Ribosome-associated heat shock protein; Implicated in the recycling of the LSU (S4 paralog). | Heat-shock chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | 0.977 |
| EEX38036.1 | hslU | VIB_000405 | VIB_000472 | Ribosome-associated heat shock protein; Implicated in the recycling of the LSU (S4 paralog). | ATP-dependent hsl protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.730 |
| EEX38036.1 | hslV | VIB_000405 | VIB_000471 | Ribosome-associated heat shock protein; Implicated in the recycling of the LSU (S4 paralog). | ATP-dependent protease HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.789 |
| EEX38036.1 | lon | VIB_000405 | VIB_001659 | Ribosome-associated heat shock protein; Implicated in the recycling of the LSU (S4 paralog). | ATP-dependent protease La Type I; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.444 |
| EEX38036.1 | pckA | VIB_000405 | VIB_000403 | Ribosome-associated heat shock protein; Implicated in the recycling of the LSU (S4 paralog). | Phosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. | 0.657 |
| EEX38037.1 | EEX38036.1 | VIB_000406 | VIB_000405 | General secretion pathway protein C. | Ribosome-associated heat shock protein; Implicated in the recycling of the LSU (S4 paralog). | 0.647 |
| EEX38037.1 | EEX38040.1 | VIB_000406 | VIB_000409 | General secretion pathway protein C. | General secretion pathway protein F. | 0.911 |
| EEX38037.1 | hslO | VIB_000406 | VIB_000404 | General secretion pathway protein C. | Heat-shock chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | 0.653 |
| EEX38037.1 | pckA | VIB_000406 | VIB_000403 | General secretion pathway protein C. | Phosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. | 0.510 |
| EEX38040.1 | EEX38036.1 | VIB_000409 | VIB_000405 | General secretion pathway protein F. | Ribosome-associated heat shock protein; Implicated in the recycling of the LSU (S4 paralog). | 0.621 |
| EEX38040.1 | EEX38037.1 | VIB_000409 | VIB_000406 | General secretion pathway protein F. | General secretion pathway protein C. | 0.911 |
| EEX38040.1 | hslO | VIB_000409 | VIB_000404 | General secretion pathway protein F. | Heat-shock chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | 0.621 |
| EEX38040.1 | pckA | VIB_000409 | VIB_000403 | General secretion pathway protein F. | Phosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. | 0.565 |
| dnaJ | EEX38036.1 | VIB_001794 | VIB_000405 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Ribosome-associated heat shock protein; Implicated in the recycling of the LSU (S4 paralog). | 0.684 |
| dnaJ | dnaK | VIB_001794 | VIB_001795 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
| dnaJ | grpE | VIB_001794 | VIB_001796 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.997 |
