| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX35697.1 | EEX36343.1 | VIB_002844 | VIB_002658 | 3-polyprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family. | FAD monooxygenase PheA/TfdB family. | 0.460 |
| EEX35697.1 | EEX38428.1 | VIB_002844 | VIB_000374 | 3-polyprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. | 0.823 |
| EEX35697.1 | betA | VIB_002844 | VIB_000018 | 3-polyprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.613 |
| EEX35697.1 | ubiA | VIB_002844 | VIB_000089 | 3-polyprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.922 |
| EEX35697.1 | ubiX | VIB_002844 | VIB_000589 | 3-polyprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family. | 3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.976 |
| EEX36343.1 | EEX35697.1 | VIB_002658 | VIB_002844 | FAD monooxygenase PheA/TfdB family. | 3-polyprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family. | 0.460 |
| EEX36343.1 | EEX38428.1 | VIB_002658 | VIB_000374 | FAD monooxygenase PheA/TfdB family. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. | 0.417 |
| EEX36343.1 | ubiX | VIB_002658 | VIB_000589 | FAD monooxygenase PheA/TfdB family. | 3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.603 |
| EEX36444.1 | ubiX | VIB_002759 | VIB_000589 | acetoacetyl-CoA synthetase. | 3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.521 |
| EEX38216.1 | EEX38217.1 | VIB_000590 | VIB_000591 | Thiamin ABC transporter substrate-binding component. | Thiamin ABC transporter transmembrane component. | 0.987 |
| EEX38216.1 | mpl | VIB_000590 | VIB_000588 | Thiamin ABC transporter substrate-binding component. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.449 |
| EEX38216.1 | ubiX | VIB_000590 | VIB_000589 | Thiamin ABC transporter substrate-binding component. | 3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.490 |
| EEX38217.1 | EEX38216.1 | VIB_000591 | VIB_000590 | Thiamin ABC transporter transmembrane component. | Thiamin ABC transporter substrate-binding component. | 0.987 |
| EEX38217.1 | mpl | VIB_000591 | VIB_000588 | Thiamin ABC transporter transmembrane component. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.449 |
| EEX38217.1 | ubiX | VIB_000591 | VIB_000589 | Thiamin ABC transporter transmembrane component. | 3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.490 |
| EEX38428.1 | EEX35697.1 | VIB_000374 | VIB_002844 | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. | 3-polyprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family. | 0.823 |
| EEX38428.1 | EEX36343.1 | VIB_000374 | VIB_002658 | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. | FAD monooxygenase PheA/TfdB family. | 0.417 |
| EEX38428.1 | ubiA | VIB_000374 | VIB_000089 | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.748 |
| EEX38428.1 | ubiX | VIB_000374 | VIB_000589 | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. | 3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.612 |
| acsA | ubiX | VIB_002854 | VIB_000589 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.521 |