Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EEX36528.1NADPH-flavin oxidoreductase; Belongs to the flavin oxidoreductase frp family. (240 aa)    
Predicted Functional Partners:
EEX38277.1
Riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family.
    
 0.894
EEX38606.1
2-haloalkanoic acid dehalogenase.
    
 0.868
ubiX
3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
     
  0.866
EEX36766.1
2,4-dienoyl-CoA reductase [NADPH].
  
 
 0.720
birA
Biotin-protein ligase/biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.720
EEX36774.1
long-chain-fatty-acid--CoA ligase.
   
   0.705
EEX37435.1
long-chain-fatty-acid--CoA ligase.
   
   0.705
EEX37453.1
O-succinylbenzoic acid--CoA ligase.
   
   0.705
EEX37096.1
Predicted hydrolase.
    
  0.665
EEX38364.1
ABC-type multidrug transport system permease component.
  
  
 0.645
Your Current Organism:
Vibrio metschnikovii
NCBI taxonomy Id: 675813
Other names: V. metschnikovii CIP 69.14, Vibrio metschnikovii CIP 69.14, Vibrio metschnikovii str. CIP 69.14, Vibrio metschnikovii strain CIP 69.14
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