STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purRPurine nucleotide synthesis repressor; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. (336 aa)    
Predicted Functional Partners:
EEX37817.1
Glutamate synthase [NADPH] large chain.
    
 
 0.885
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
    
   0.595
EEX35967.1
Fructose-specific phosphocarrier protein HPr/PTS system fructose-specific IIA component.
   
 
 0.593
EEX37599.1
Phosphocarrier protein of PTS system.
 
 
 
 0.575
EEX38458.1
PTS system maltose and glucose-specific IIBC component.
    
 0.553
EEX37397.1
Phosphotransferase system sucrose-specific IIBC component.
    
 0.553
EEX37481.1
Phosphotransferase system glucose-specific IIBC component.
    
 0.553
EEX37577.1
Phosphotransferase system N-acetylglucosamine-specific IIBC component.
    
 0.553
EEX37624.1
Phosphotransferase system trehalose-specific IIBC component.
    
 0.553
EEX35752.1
PTS system alpha-glucoside-specific IIBC component.
    
 0.553
Your Current Organism:
Vibrio metschnikovii
NCBI taxonomy Id: 675813
Other names: V. metschnikovii CIP 69.14, Vibrio metschnikovii CIP 69.14, Vibrio metschnikovii str. CIP 69.14, Vibrio metschnikovii strain CIP 69.14
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.