| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX35891.1 | queE | VIB_002203 | VIB_001211 | Hypothetical protein. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.808 |
| EEX35972.1 | EEX38361.1 | VIB_002284 | VIB_000307 | Ribonucleotide reductase of class III (anaerobic) large subunit. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.484 |
| EEX35972.1 | queE | VIB_002284 | VIB_001211 | Ribonucleotide reductase of class III (anaerobic) large subunit. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.808 |
| EEX37099.1 | queC | VIB_001213 | VIB_001212 | Hypothetical protein. | Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.503 |
| EEX37099.1 | queE | VIB_001213 | VIB_001211 | Hypothetical protein. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.490 |
| EEX37245.1 | folE | VIB_001363 | VIB_002344 | Queuosine biosynthesis QueD PTPS-I. | GTP cyclohydrolase I type 1. | 0.876 |
| EEX37245.1 | queC | VIB_001363 | VIB_001212 | Queuosine biosynthesis QueD PTPS-I. | Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.963 |
| EEX37245.1 | queE | VIB_001363 | VIB_001211 | Queuosine biosynthesis QueD PTPS-I. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.987 |
| EEX37245.1 | queF | VIB_001363 | VIB_001756 | Queuosine biosynthesis QueD PTPS-I. | NADPH dependent preQ0 reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.837 |
| EEX38361.1 | EEX35972.1 | VIB_000307 | VIB_002284 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Ribonucleotide reductase of class III (anaerobic) large subunit. | 0.484 |
| EEX38361.1 | folE | VIB_000307 | VIB_002344 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | GTP cyclohydrolase I type 1. | 0.992 |
| EEX38361.1 | queE | VIB_000307 | VIB_001211 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.501 |
| folE | EEX37245.1 | VIB_002344 | VIB_001363 | GTP cyclohydrolase I type 1. | Queuosine biosynthesis QueD PTPS-I. | 0.876 |
| folE | EEX38361.1 | VIB_002344 | VIB_000307 | GTP cyclohydrolase I type 1. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.992 |
| folE | queC | VIB_002344 | VIB_001212 | GTP cyclohydrolase I type 1. | Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.414 |
| folE | queE | VIB_002344 | VIB_001211 | GTP cyclohydrolase I type 1. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.615 |
| folE | queF | VIB_002344 | VIB_001756 | GTP cyclohydrolase I type 1. | NADPH dependent preQ0 reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.469 |
| glmS | purF | VIB_002054 | VIB_001694 | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.689 |
| glmS | queC | VIB_002054 | VIB_001212 | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.578 |
| glmS | queE | VIB_002054 | VIB_001211 | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.623 |