STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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[Homology]
Score
EEX37138.1Ferric siderophore transport system binding protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (206 aa)    
Predicted Functional Partners:
EEX37137.1
Biopolymer transport protein ExbD/TolR.
 
 
 0.996
EEX37136.1
MotA/TolQ/ExbB proton channel family protein.
 
 
 0.963
EEX37139.1
tPR domain protein putative component of TonB system.
 
 
   0.952
tolR
Tol biopolymer transport system TolR protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.951
EEX36328.1
Receptor protein mostly Fe transport.
 
 
 0.929
EEX36354.1
TonB-dependent heme and hemoglobin receptor HutA; Most likely function alternative not yet resolved; TonB-dependent hemin ferrichrome receptor.
 
 
 0.927
tolQ
MotA/TolQ/ExbB proton channel family protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.921
EEX37412.1
TonB-dependent heme receptor.
  
 
 0.914
btuB
Outer membrane vitamin B12 receptor BtuB; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
   
 
 0.894
EEX36375.1
Outer membrane lipoprotein.
    
   0.873
Your Current Organism:
Vibrio metschnikovii
NCBI taxonomy Id: 675813
Other names: V. metschnikovii CIP 69.14, Vibrio metschnikovii CIP 69.14, Vibrio metschnikovii str. CIP 69.14, Vibrio metschnikovii strain CIP 69.14
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