Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EEX37220.1PrpF protein involved in 2-methylcitrate cycle. (411 aa)    
Predicted Functional Partners:
EEX37221.1
2-methylcitrate dehydratase FeS dependent.
 
 
 0.999
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
  
 0.962
EEX38354.1
Aconitate hydratase 2; Enzyme with broad specificity; 2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family.
    
 0.937
EEX37222.1
2-methylcitrate synthase; Belongs to the citrate synthase family.
 
  
 0.930
EEX37224.1
Propionate catabolism operon transcriptional regulator of GntR family.
 
  
 0.823
EEX36343.1
FAD monooxygenase PheA/TfdB family.
  
  
  0.728
ubiX
3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
     
  0.719
EEX36824.1
NADH oxidoreductase Hcr.
     
  0.703
EEX36103.1
Flavodoxin reductases, family 1.
     
  0.703
EEX35697.1
3-polyprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family.
     
  0.651
Your Current Organism:
Vibrio metschnikovii
NCBI taxonomy Id: 675813
Other names: V. metschnikovii CIP 69.14, Vibrio metschnikovii CIP 69.14, Vibrio metschnikovii str. CIP 69.14, Vibrio metschnikovii strain CIP 69.14
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