STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (299 aa)    
Predicted Functional Partners:
EEX37222.1
2-methylcitrate synthase; Belongs to the citrate synthase family.
 
 0.985
EEX37221.1
2-methylcitrate dehydratase FeS dependent.
 
 0.966
EEX37220.1
PrpF protein involved in 2-methylcitrate cycle.
 
  
 0.912
EEX36698.1
Citrate synthase (si); Belongs to the citrate synthase family.
 
 0.902
EEX37224.1
Propionate catabolism operon transcriptional regulator of GntR family.
 
  
 0.878
EEX36822.1
Alcohol dehydrogenase; Most likely function alternative not yet resolved; acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.859
EEX36753.1
Pyruvate-flavodoxin oxidoreductase.
    
  0.833
EEX38354.1
Aconitate hydratase 2; Enzyme with broad specificity; 2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family.
    
 0.827
EEX36402.1
Malate synthase-related protein.
  
 
 0.810
EEX37238.1
Fumarate hydratase class I aerobic.
    
 0.808
Your Current Organism:
Vibrio metschnikovii
NCBI taxonomy Id: 675813
Other names: V. metschnikovii CIP 69.14, Vibrio metschnikovii CIP 69.14, Vibrio metschnikovii str. CIP 69.14, Vibrio metschnikovii strain CIP 69.14
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.